Tools to analyze the tumor environment in cancer patients
Analytical tools for studying the tumor microenvironment leveraging spatial transcriptomics
This study is looking at how the environment around tumors affects cancer treatment, especially immunotherapy, to help doctors find the best personalized options for patients based on their unique tumor characteristics.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-10914196 on NIH RePORTER |
What this research studies
This research focuses on understanding the tumor microenvironment (TME) to better identify cancer patients who may respond to immunotherapy. It utilizes advanced techniques called spatial transcriptomics, which allow researchers to see how individual cells are arranged within the tumor tissue. By developing new computational tools to analyze this complex data, the research aims to provide insights into the biological significance of the TME and improve cancer treatment strategies. Patients may benefit from more personalized treatment options based on their tumor characteristics.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients undergoing immunotherapy or those with tumors that can be analyzed using spatial transcriptomics.
Not a fit: Patients with non-cancerous conditions or those not receiving immunotherapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments for patients.
How similar studies have performed: Other research has shown promise using spatial transcriptomics, indicating that this approach could lead to significant advancements in understanding cancer biology.
Where this research is happening
Tampa, United States
- H. Lee Moffitt Cancer Ctr & Res Inst — Tampa, United States (Active)
Researchers
- Principal investigator: Yu, Xiaoqing — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Yu, Xiaoqing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.