Tools for studying RNA modifications and their roles in cells
A chemical biology toolbox for RNA post-transcriptional modification and capture
['FUNDING_OTHER'] · WASHINGTON UNIVERSITY · NIH-11075314
This study is looking at how RNA, which is important for our genes, gets changed after it's made, and it aims to find new ways to see and study these changes in living cells, which could help improve tests and treatments for diseases.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11075314 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how RNA, which carries genetic information, is modified after it is created. It aims to develop new methods to label and visualize specific RNAs in living cells, as well as to capture and analyze edited RNA transcripts. By addressing current technological limitations, the project seeks to enhance our understanding of RNA's role in cellular processes and its implications in various diseases. Patients may benefit from advancements in diagnostics and therapeutics that arise from these findings.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions linked to RNA processing and modification disorders.
Not a fit: Patients with conditions unrelated to RNA biology or those not affected by RNA dysregulation may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new diagnostic tools and treatments for diseases related to RNA dysregulation.
How similar studies have performed: Other research has shown promise in developing technologies for RNA analysis, indicating potential success for this approach.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HEEMSTRA, JENNIFER MARGARET — WASHINGTON UNIVERSITY
- Study coordinator: HEEMSTRA, JENNIFER MARGARET
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.