NIH-funded research NIH-funded research

Tobacco use patterns in Appalachian Kentucky adults

Official title: AppalTRuST Project 1: Population based Cohort study of tobacco use prevalence in Appalachian KY

Funded at University of Kentucky · NIH-11163563 · Data updated 2026-11-12

This project follows adults in Appalachian Kentucky to track tobacco use, attitudes, and exposures over time to see how FDA tobacco rules affect people in rural communities.

More Tobacco Use research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Kentucky
NIH-funded
Lab location1 site (Lexington, United States)
Project startSeptember 30, 2023
Project endAugust 31, 2028
Funding year2025
Award (this year)$250,736
NIH project number5U54DA058256-03
Project IDNIH-11163563 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 18 and older who live in the study catchment counties in Appalachian Kentucky and can complete surveys every six months are ideal candidates.

Less likely to help

People who live outside the selected Appalachian Kentucky counties or who are under 18 would not be eligible to join and are unlikely to directly benefit from participation.

What this research studies

You would be part of a group of about 2,000 adults from eight counties in Appalachian Kentucky who are asked about tobacco use every six months for four years. The project compares two catchment areas with different levels of rurality to understand how local context affects use. Questions will cover knowledge, attitudes, perceptions, and external cues using the Health Belief Model to link beliefs with tobacco behaviors. Data will be used to inform how FDA tobacco regulations might impact rural populations.

Why it matters

Potential benefit: If successful, the findings could help shape FDA and local policies to better reduce tobacco use and exposure in rural Appalachian communities.

How similar studies have gone: Long-term cohort studies have informed tobacco policy in the past, but dedicated longitudinal work focused on rural Appalachian populations has been less common.

Where this research is happening

  • University of Kentucky
    Lexington, United States
    Active

Researchers

  • Principal investigator: Rayens, Mary Kay — University of Kentucky
  • Study coordinator: Rayens, Mary Kay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.