Tissue and sample resource for people with Barrett's Esophagus
Bioreagents & Resources Core
['FUNDING_P01'] · CASE WESTERN RESERVE UNIVERSITY · NIH-11179403
Provides high-quality tissue and blood samples plus expert pathology support to help research on Barrett's Esophagus and related esophageal cancers.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CASE WESTERN RESERVE UNIVERSITY (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-11179403 on ClinicalTrials.gov |
What this research studies
This core collects, curates, and shares well-annotated tissue and blood specimens from people with Barrett's Esophagus and related esophageal conditions. Expert gastrointestinal pathologists review and annotate the samples and offer pathology consultation to research teams. The resource leverages long-standing bioarchives at Case Western Reserve and Duke with over 6,200 patient specimens and links clinical data to the samples. Shared specimens and reagents are supplied to multiple projects to enable translational and basic science work, including creation of animal models when needed.
Who could benefit from this research
Good fit: People with a diagnosis of Barrett's Esophagus or related esophageal neoplasia who can donate tissue or blood samples or allow use of their archived specimens are the ideal candidates.
Not a fit: Individuals without Barrett's Esophagus or those unwilling/unable to provide or permit use of tissue or blood samples are unlikely to benefit directly from this core.
Why it matters
Potential benefit: By making high-quality, well-annotated samples widely available, the core could speed discovery of causes, biomarkers, and treatments for Barrett's Esophagus and esophageal cancer.
How similar studies have performed: Biorepository and pathology core models like this have a long track record of enabling important discoveries in Barrett's Esophagus and esophageal cancer.
Where this research is happening
CLEVELAND, UNITED STATES
- CASE WESTERN RESERVE UNIVERSITY — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WILLIS, JOSEPH EDWARD — CASE WESTERN RESERVE UNIVERSITY
- Study coordinator: WILLIS, JOSEPH EDWARD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Barrett Syndrome