Tiny Scavengers for Parkinson's Disease
CSF Oligomeric α-synuclein targeted nano scavengers as a Parkinson's disease theranostic
['FUNDING_R01'] · BAYLOR COLLEGE OF MEDICINE · NIH-11194438
This project aims to develop tiny particles that can find and remove harmful proteins in the brain to help people with Parkinson's disease.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11194438 on ClinicalTrials.gov |
What this research studies
Parkinson's disease involves the buildup of harmful protein clumps called alpha-synuclein in the brain, which leads to nerve damage and symptoms. Currently, there are no effective ways to diagnose Parkinson's early or treatments that can stop the disease from getting worse. This research is creating special nanoparticles designed to cross into the brain's fluid, locate these harmful protein clumps, and remove them. These nanoparticles could potentially serve as both an early detection tool and a new treatment to slow or halt the disease's progression. This approach builds on recent successes in Alzheimer's disease where similar strategies have shown promise in slowing disease progression.
Who could benefit from this research
Good fit: This early-stage research is not directly recruiting patients, but future studies might seek individuals with Parkinson's disease or those at risk.
Not a fit: Patients currently seeking immediate treatment options would not directly benefit from this foundational laboratory research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and a new treatment to slow or stop the progression of Parkinson's disease.
How similar studies have performed: While this specific nanoparticle approach is novel for Parkinson's, similar strategies using antibodies have shown promise in slowing Alzheimer's disease.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TANIFUM, ERIC — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: TANIFUM, ERIC
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, Alzheimer's disease model