Therapeutics to promote brain health as we age
Mitochondrial therapeutics for healthy brain aging
This study is looking for new ways to keep our brains healthy as we get older by finding drugs that help the energy centers in our brain cells work better, and it will test these treatments in animals to see if they can help prevent memory and mental health problems in older adults.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10904993 on NIH RePORTER |
What this research studies
This research focuses on developing new treatments that can help maintain brain health and cognitive function as people age. By targeting mitochondria, the energy-producing structures in brain cells, the researchers aim to identify and optimize drugs that can enhance mitochondrial function. These potential treatments will be tested in laboratory animals to assess their effectiveness in preventing cognitive decline and mental health issues associated with aging. The ultimate goal is to pave the way for future clinical applications that could benefit older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who are experiencing or are at risk for cognitive decline and mental health issues.
Not a fit: Patients who are not experiencing age-related cognitive decline or who are younger than 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve brain health and cognitive function in older adults.
How similar studies have performed: Previous research has shown promise in enhancing mitochondrial function as a strategy for improving brain health, indicating that this approach may be viable.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Davis, Ronald L — University of Florida
- Study coordinator: Davis, Ronald L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.