The role of gut bacteria in cognitive issues related to Parkinson's disease
Microbiome Composition and Function Contributes to Cognitive Impairment and Neuroinflammation in Parkinson’s Disease
This study is looking at how the bacteria in your gut might affect thinking and memory problems in people with Parkinson's disease, hoping to find new ways to help improve these symptoms.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California State Univ San Bernardino NIH-funded |
| Lab location | 1 site (San Bernardino, United States) |
| Project ID | NIH-10828333 on NIH RePORTER |
What this research studies
This research investigates how the composition of gut bacteria may influence cognitive impairment and neuroinflammation in individuals with Parkinson's disease. It explores the connection between changes in gut microbiota and cognitive decline, aiming to identify alternative mechanisms that contribute to these symptoms. By analyzing the gut environment and its relationship with cognitive function, the study seeks to uncover new treatment targets and improve prognostic predictions for patients. The research employs a combination of clinical assessments and microbiome analysis to understand these complex interactions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who are experiencing cognitive impairment.
Not a fit: Patients without a diagnosis of Parkinson's disease or those not experiencing cognitive issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that improve cognitive function in patients with Parkinson's disease.
How similar studies have performed: Previous research has shown promising results linking gut microbiota to cognitive function, suggesting that this approach may yield valuable insights.
Where this research is happening
San Bernardino, United States
- California State Univ San Bernardino — San Bernardino, United States (Active)
Researchers
- Principal investigator: Jones, Jacob D — California State Univ San Bernardino
- Study coordinator: Jones, Jacob D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.