The role of different BRD4 protein forms in breast cancer
Opposing Functions of BRD4 Isoforms in Breast Cancer
This study is looking at how different versions of a protein called BRD4 impact breast cancer cells, with the hope of finding new ways to treat the disease and create better, personalized therapies for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10832004 on NIH RePORTER |
What this research studies
This research investigates how different forms of the BRD4 protein affect breast cancer cells. By understanding the specific roles of these protein isoforms, researchers aim to identify potential therapeutic targets for treatment. The study utilizes advanced techniques to manipulate and observe the effects of BRD4 isoforms on cancer cell behavior, which could lead to more personalized treatment strategies. The findings may help in developing new drugs that specifically target these proteins to improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with breast cancer, particularly those with specific genetic or epigenetic profiles.
Not a fit: Patients with non-breast cancer malignancies or those whose cancer does not involve BRD4 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for breast cancer patients.
How similar studies have performed: Previous research has shown promising results with similar approaches targeting BRD4 in cancer treatment, indicating a potential for success in this area.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Chiang, Cheng-Ming — Ut Southwestern Medical Center
- Study coordinator: Chiang, Cheng-Ming
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.