The role of dietary fiber and soy protein in preventing inflammatory bowel disease.
Dietary fiber and soy protein-based microbiome metabolites for IBD prevention
This study looks at how eating more fiber and soy protein might help keep your gut healthy and reduce the risk of inflammatory bowel disease (IBD) by looking at how these foods affect gut bacteria and the protective layer in your intestines.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11000796 on NIH RePORTER |
What this research studies
This research investigates how dietary fiber and soy protein influence the gut microbiome and its metabolites in relation to inflammatory bowel disease (IBD). Using a specialized mouse model that mimics the human gut microbiota, the study explores the interactions between diet, gut bacteria, and the protective mucus barrier in the intestines. By understanding these connections, researchers aim to identify how dietary choices can impact the risk of developing IBD and improve gut health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for inflammatory bowel disease, including those with a family history or genetic predisposition.
Not a fit: Patients who already have established inflammatory bowel disease may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to dietary recommendations that help prevent or manage inflammatory bowel disease.
How similar studies have performed: Previous research has shown promising results in understanding the role of diet and gut microbiota in gastrointestinal health, suggesting potential for success in this area.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Martens, Eric C — University of Michigan at Ann Arbor
- Study coordinator: Martens, Eric C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.