The role of a specific neuropeptide in hearing and balance issues related to migraines
CGRP's effect on hearing and balance in a mouse model of migraine
This study is looking at how a specific protein related to migraines might impact hearing and balance in mice, with the hope of finding better treatments for people who experience dizziness and balance problems along with their migraines.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10434800 on NIH RePORTER |
What this research studies
This research investigates how calcitonin gene-related peptide (CGRP) affects hearing and balance in a mouse model of migraine. It focuses on understanding the connection between migraines and vestibular symptoms, such as dizziness and balance problems, which affect a significant number of migraine patients. By using genetically modified mice that are sensitive to CGRP, the researchers aim to explore the mechanisms behind these symptoms and test potential treatments. The findings could lead to better therapeutic options for those suffering from migraines and associated balance issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who suffer from migraines, particularly those experiencing vestibular symptoms like dizziness.
Not a fit: Patients who do not experience migraines or related balance issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for migraine patients who also experience balance and hearing problems.
How similar studies have performed: Previous research has shown promising results in understanding the role of CGRP in migraines, indicating that this approach could yield valuable insights.
Where this research is happening
Rochester, United States
- University of Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Luebke, Anne E — University of Rochester
- Study coordinator: Luebke, Anne E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.