The relationship between oral bacteria and tooth decay in children with HIV
Oral Microbiomes and Dental Caries in a Human Immunodeficiency Virus Infected Population
This study looks at how the germs in the mouths of children with HIV might affect their risk of getting cavities, and it aims to find ways to help keep their teeth healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Clemson University NIH-funded |
| Lab location | 1 site (Clemson, United States) |
| Project ID | NIH-10424444 on NIH RePORTER |
What this research studies
This research investigates how the oral microbiome, which consists of various bacteria and fungi, affects dental caries (tooth decay) in children infected with HIV. It focuses on understanding the differences in the composition of oral bacteria between healthy children and those with HIV, particularly those undergoing treatment. By analyzing dental plaque and gene expression, the study aims to identify specific microbial changes that may contribute to increased tooth decay in this vulnerable population. The findings could lead to improved prevention and treatment strategies for maintaining oral health in HIV-infected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are infected with HIV and may be experiencing dental caries.
Not a fit: Patients who are not infected with HIV or who are outside the age range of 0-11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better oral health outcomes and targeted prevention strategies for children living with HIV.
How similar studies have performed: Previous studies have shown significant changes in the oral microbiome related to health conditions, indicating that this research approach has potential for success.
Where this research is happening
Clemson, United States
- Clemson University — Clemson, United States (Active)
Researchers
- Principal investigator: Richards, Vincent — Clemson University
- Study coordinator: Richards, Vincent
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.