The relationship between gut bacteria and kidney injury recovery
Acute kidney injury and microbiome
This study is looking at how the bacteria in your gut might help your kidneys heal after an injury, and it’s for anyone interested in understanding how gut health can affect kidney recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10835927 on NIH RePORTER |
What this research studies
This research investigates how the gut microbiome influences recovery from acute kidney injury (AKI). It aims to understand the mechanisms of communication between gut bacteria and kidney cells, particularly focusing on immune responses during the recovery phase. The study will involve analyzing immune cells in mice with different gut microbiota conditions and measuring specific metabolites produced by gut bacteria that may affect kidney function. By exploring these interactions, the research seeks to uncover potential therapeutic targets for improving kidney recovery.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced acute kidney injury and may benefit from interventions targeting the gut microbiome.
Not a fit: Patients with chronic kidney disease or those who have not experienced acute kidney injury may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance recovery from acute kidney injury by modulating gut bacteria.
How similar studies have performed: Other research has shown promising results in understanding the role of the microbiome in various health conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Rabb, Hamid — Johns Hopkins University
- Study coordinator: Rabb, Hamid
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.