The relationship between gut bacteria and heart health in people with inflammatory bowel disease.

Gut Dysbiosis and Cardiac Remodeling in IBD

NIH-funded research University of Texas Med Br Galveston · NIH-10687085

This study is looking at how changes in gut bacteria might affect heart health in people with inflammatory bowel disease (IBD), aiming to find new ways to help those who may face both gut and heart problems.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Med Br Galveston NIH-funded
Lab location1 site (Galveston, United States)
Project IDNIH-10687085 on NIH RePORTER

What this research studies

This research investigates how changes in gut bacteria, known as dysbiosis, may contribute to heart problems in individuals suffering from inflammatory bowel disease (IBD). By studying both human and animal models, the research aims to uncover the molecular mechanisms linking gut health and cardiovascular diseases. Patients with IBD may experience not only gastrointestinal symptoms but also increased risks of heart issues, which this research seeks to address. The study will involve analyzing gut microbiota and its effects on heart function, potentially leading to new treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with inflammatory bowel disease.

Not a fit: Patients without inflammatory bowel disease or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved management of heart health in patients with inflammatory bowel disease.

How similar studies have performed: Previous research has indicated a connection between gut microbiota and cardiovascular health, suggesting that this approach may yield valuable insights.

Where this research is happening

Galveston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.