The relationship between arterial stiffness and brain health in U.S. Hispanics/Latinos
Official title: Arterial stiffness, brain morphology, cognition, and dementia in U.S. Hispanics/Latinos
Funded at Univ of North Carolina Chapel Hill · NIH-10318668 · Data updated 2026-11-12
This study is looking at how stiff arteries might impact brain health and thinking skills, especially in older Hispanic/Latino adults, to see if there’s a link between heart health and conditions like Alzheimer's disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | February 15, 2019 |
| Project end | November 30, 2025 |
| Funding year | 2022 |
| Award (this year) | $736,359 |
| NIH project number | 5R01AG061088-04 |
| Project ID | NIH-10318668 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are U.S. Hispanics/Latinos aged 45 and older who may be at risk for cognitive impairment or Alzheimer's disease.
✕Less likely to help
Patients who are younger than 45 years old or who do not identify as Hispanic/Latino may not benefit from this research.
What this research studies
This research investigates how arterial stiffness may affect brain structure and function, particularly in relation to cognitive impairment and Alzheimer's disease among U.S. Hispanics/Latinos. By measuring arterial stiffness using a non-invasive technique called pulse wave velocity, the study aims to understand the connections between cardiovascular health and brain health in this population. The research will analyze data from a large cohort of Hispanic/Latino participants aged 45 and older, focusing on factors such as sex, obesity, and diabetes that may influence these relationships.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for cognitive decline and Alzheimer's disease in Hispanic/Latino communities.
How similar studies have gone: Previous research has shown promising results in understanding the links between cardiovascular health and cognitive decline, but this specific focus on Hispanic/Latino populations is relatively novel.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Meyer, Michelle — Univ of North Carolina Chapel Hill
- Study coordinator: Meyer, Michelle
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.