The relationship between arterial stiffness and brain health in U.S. Hispanics/Latinos

Arterial stiffness, brain morphology, cognition, and dementia in U.S. Hispanics/Latinos

['FUNDING_R01'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-10318668

This study is looking at how stiff arteries might impact brain health and thinking skills, especially in older Hispanic/Latino adults, to see if there’s a link between heart health and conditions like Alzheimer's disease.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIV OF NORTH CAROLINA CHAPEL HILL (nih funded)
Locations1 site (CHAPEL HILL, UNITED STATES)
Trial IDNIH-10318668 on ClinicalTrials.gov

What this research studies

This research investigates how arterial stiffness may affect brain structure and function, particularly in relation to cognitive impairment and Alzheimer's disease among U.S. Hispanics/Latinos. By measuring arterial stiffness using a non-invasive technique called pulse wave velocity, the study aims to understand the connections between cardiovascular health and brain health in this population. The research will analyze data from a large cohort of Hispanic/Latino participants aged 45 and older, focusing on factors such as sex, obesity, and diabetes that may influence these relationships.

Who could benefit from this research

Good fit: Ideal candidates for this research are U.S. Hispanics/Latinos aged 45 and older who may be at risk for cognitive impairment or Alzheimer's disease.

Not a fit: Patients who are younger than 45 years old or who do not identify as Hispanic/Latino may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for cognitive decline and Alzheimer's disease in Hispanic/Latino communities.

How similar studies have performed: Previous research has shown promising results in understanding the links between cardiovascular health and cognitive decline, but this specific focus on Hispanic/Latino populations is relatively novel.

Where this research is happening

CHAPEL HILL, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer's Disease, Alzheimer disease, Alzheimer syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.