The long-term effects of low dose aspirin on cancer and overall health in older adults
Aspirins legacy on cancer and overall benefit: risk balance over a 15-year horizon
This study is looking at whether taking low dose aspirin can help prevent cancer and improve health for older adults aged 65 and up, while also checking for any risks like heart issues or stomach problems.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11190013 on NIH RePORTER |
What this research studies
This research investigates the role of low dose aspirin in preventing cancer and improving overall health outcomes in older adults, particularly those aged 65 and over. It aims to fill gaps in existing knowledge by evaluating the long-term effects of aspirin on colorectal cancer incidence and mortality, as well as its impact on cardiovascular disease risk and gastrointestinal bleeding. The study will also enhance risk prediction models to ensure they are applicable to diverse populations. By analyzing data over a 15-year horizon, the research seeks to determine the overall health benefit versus risk of aspirin use in this age group.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 65 and older who are at risk for cancer and cardiovascular diseases.
Not a fit: Patients under the age of 65 or those with contraindications to aspirin use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide valuable insights into how low dose aspirin may help prevent cancer and improve health outcomes for older adults.
How similar studies have performed: Previous studies have shown promising results regarding the benefits of low dose aspirin in older populations, suggesting that this research builds on established findings.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Warner, Erica T — Massachusetts General Hospital
- Study coordinator: Warner, Erica T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.