The link between vitamin A levels and schistosomiasis in young children in Uganda
Official title: Vitamin A Status and its Relationship to S. mansoni Infection Intensity and Environmental Enteric Dysfunction in Preschool-Aged Children Receiving Treatment for Schistosomiasis in Uganda
Funded at Rhode Island Hospital · NIH-10975855 · Data updated 2026-11-12
This study is looking at how not getting enough vitamin A might make schistosomiasis and gut problems worse in young children being treated for schistosomiasis in Uganda, and it hopes to find ways to use nutrition to help improve their health.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rhode Island Hospital NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project start | December 12, 2023 |
| Project end | December 11, 2026 |
| Funding year | 2025 |
| Award (this year) | $81,256 |
| NIH project number | 5F32AI176721-02 |
| Project ID | NIH-10975855 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are preschool-aged children in Uganda who are being treated for schistosomiasis and may be experiencing vitamin A deficiency.
✕Less likely to help
Patients who are not preschool-aged or those not affected by schistosomiasis or environmental enteric dysfunction may not benefit from this research.
What this research studies
This research investigates how vitamin A deficiency affects the severity of schistosomiasis and environmental enteric dysfunction in preschool-aged children undergoing treatment for schistosomiasis in Uganda. By examining the relationship between vitamin A status and these health issues, the study aims to identify potential nutrition-based interventions that could alleviate infection-related health problems. The research employs a combination of clinical assessments and innovative methods to measure vitamin A levels in children with schistosomiasis, providing insights into the underlying mechanisms of these conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved nutritional strategies that reduce the health impacts of schistosomiasis and environmental enteric dysfunction in young children.
How similar studies have gone: Previous research has shown promising results in understanding the role of vitamin A in infection and growth, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Rhode Island Hospital
Providence, United States Active
Researchers
- Principal investigator: Colt, Susannah — Rhode Island Hospital
- Study coordinator: Colt, Susannah
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.