The link between sleep duration and cognitive function in older adults
Sleep duration Polygenic Risk Score: Association with cognition and brain measures
This study is looking at how the amount of sleep you get can affect your thinking skills and brain health as you get older, especially if you have concerns about memory or conditions like Alzheimer's, and it will explore how your genes might play a role in this relationship.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10682381 on NIH RePORTER |
What this research studies
This research investigates how sleep duration affects cognitive abilities and brain health, particularly in older adults. It focuses on understanding the genetic factors that may influence sleep patterns and their relationship with cognitive decline and neurodegenerative diseases like Alzheimer's. By analyzing polygenic risk scores, the study aims to identify how variations in genes related to sleep can impact cognitive performance and brain structure. Participants may undergo assessments of their sleep habits, cognitive function, and brain imaging to gather comprehensive data.
Who could benefit from this research
Good fit: Ideal candidates for this research are cognitively healthy adults aged 65 and older who may be experiencing sleep disturbances.
Not a fit: Patients with severe cognitive impairments or those currently diagnosed with advanced neurodegenerative diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing cognitive decline and enhancing brain health in older adults.
How similar studies have performed: Previous research has shown promising results linking sleep patterns and cognitive function, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Tsapanou, Angeliki — Columbia University Health Sciences
- Study coordinator: Tsapanou, Angeliki
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.