The link between short sleep and methamphetamine use in women
Short Sleep Duration as a Predictor of Methamphetamine Intake: Role of Orexin Mechanisms
This study looks at how not getting enough sleep might make women more likely to use methamphetamine, focusing on a brain chemical called orexin that helps control sleep. By watching female monkeys, researchers hope to understand how sleep and drug use are connected, which could help us find better ways to treat addiction.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Mississippi Med Ctr NIH-funded |
| Lab location | 1 site (Jackson, United States) |
| Project ID | NIH-11138772 on NIH RePORTER |
What this research studies
This research investigates how insufficient sleep may lead to increased methamphetamine intake, particularly focusing on adult females. The study examines the role of orexin, a brain chemical that regulates sleep, in influencing sleep patterns and substance use behaviors. By observing the sleep and drug intake patterns in female rhesus monkeys, researchers aim to uncover biological mechanisms that could explain the connection between sleep duration and addiction. The findings could provide insights into how sleep quality affects addiction risk and inform potential treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are adult females who experience short sleep duration and may be at risk for methamphetamine use or addiction.
Not a fit: Patients who do not have issues with sleep duration or are not at risk for methamphetamine use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new interventions for preventing or treating methamphetamine addiction by addressing sleep issues.
How similar studies have performed: Previous research has indicated a connection between sleep patterns and substance use, suggesting that this approach could yield valuable insights.
Where this research is happening
Jackson, United States
- University of Mississippi Med Ctr — Jackson, United States (Active)
Researchers
- Principal investigator: Berro, Lais F — University of Mississippi Med Ctr
- Study coordinator: Berro, Lais F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.