The link between pregnancy-related high blood pressure and future heart disease in women

Hypertensive pregnancy disorders and future coronary artery disease

NIH-funded research Mayo Clinic Rochester · NIH-10452767

This study is looking at how having high blood pressure during pregnancy, like preeclampsia, might raise the chances of women developing heart disease later on, and it aims to find out what specific factors are involved so we can help catch and prevent heart issues earlier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10452767 on NIH RePORTER

What this research studies

This research investigates how hypertensive pregnancy disorders, particularly preeclampsia, may increase the risk of developing coronary artery disease (CAD) later in life for women. It aims to understand the unique risk factors associated with these pregnancy complications and how they contribute to heart disease, which is a leading cause of death among women. The study will analyze the severity of atherosclerosis in women with a history of hypertensive pregnancy disorders compared to those without. By examining these relationships, the research seeks to improve early detection and prevention strategies for CAD in women.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who have experienced hypertensive pregnancy disorders, such as preeclampsia, during their pregnancies.

Not a fit: Patients who have not experienced any hypertensive disorders during pregnancy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better screening and preventive measures for heart disease in women who have experienced hypertensive pregnancy disorders.

How similar studies have performed: Previous research has indicated that pregnancy-related complications can influence long-term cardiovascular health, suggesting that this study builds on established findings in the field.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions disease onsetdisorder onset
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.