The link between fat in muscles and diabetes in veterans with HIV
Ectopic Lipid in Skeletal Muscle is Associated with Glucose Intolerance in Veterans with HIV
This study is looking at how extra fat in the muscles might affect blood sugar control in veterans with HIV, helping us understand how obesity and HIV together can lead to issues like insulin resistance and diabetes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10841525 on NIH RePORTER |
What this research studies
This research investigates how the accumulation of fat in skeletal muscles affects glucose tolerance in veterans living with HIV. It focuses on understanding the relationship between obesity, HIV, and the presence of ectopic fat in muscles, which may contribute to insulin resistance and diabetes. By examining these factors, the study aims to uncover the underlying mechanisms that lead to metabolic complications in this population. The research involves analyzing muscle tissue and metabolic responses in veterans receiving treatment for HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans diagnosed with HIV who are also experiencing obesity or overweight issues.
Not a fit: Patients without HIV or those who are not overweight or obese may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing diabetes and metabolic health in veterans with HIV.
How similar studies have performed: While there has been research on liver fat and diabetes in HIV, the specific focus on muscle fat in this context is relatively novel and has not been extensively studied.
Where this research is happening
Nashville, United States
- Veterans Health Administration — Nashville, United States (Active)
Researchers
- Principal investigator: Silver, Heidi Jaye — Veterans Health Administration
- Study coordinator: Silver, Heidi Jaye
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.