The link between early life blood sugar levels and Alzheimer's disease markers in middle age.
Early life glycemic status and Alzheimer's disease neuroimaging markers in middle age: the Bogalusa Heart Study
This study is looking at how blood sugar levels in early life might affect brain health and the risk of Alzheimer's disease later on, and it's for middle-aged people who want to understand how their early life health could impact their memory and thinking in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-10535457 on NIH RePORTER |
What this research studies
This research investigates how glycemic status during early life may influence the development of Alzheimer's disease neuroimaging markers in middle-aged individuals. By examining the relationship between metabolic dysfunction and brain health, the study aims to identify potential risk factors that could be modified to prevent cognitive decline. Participants will undergo neuroimaging and assessments to evaluate brain changes associated with early life blood sugar levels. The findings could provide insights into how early interventions might mitigate the risk of Alzheimer's disease later in life.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who experienced metabolic dysfunction or abnormal glycemic levels during childhood or adolescence.
Not a fit: Patients who have not experienced any metabolic dysfunction or who are not at risk for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to strategies for preventing Alzheimer's disease by addressing early life metabolic health.
How similar studies have performed: Previous research has indicated that early life factors can significantly impact long-term cognitive health, suggesting that this approach may yield valuable insights.
Where this research is happening
New Orleans, United States
- Tulane University of Louisiana — New Orleans, United States (Active)
Researchers
- Principal investigator: Bazzano, Lydia — Tulane University of Louisiana
- Study coordinator: Bazzano, Lydia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.