The link between early life adversities and uterine fibroids in women

Early Life Adversities and the Risk of Uterine Fibroids

NIH-funded research Univ of North Carolina Chapel Hill · NIH-10988529

This study is looking at how tough experiences in childhood might lead to a higher chance of getting uterine fibroids, especially in Black women aged 23-34, and it will also explore how support and coping skills can help reduce these risks.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-10988529 on NIH RePORTER

What this research studies

This research investigates how early life adversities, such as childhood trauma, may increase the risk of developing uterine fibroids, particularly in Black/African American women. By analyzing data from a large cohort of women aged 23-34, the study aims to identify the prevalence of adverse childhood events and their association with fibroid development and growth. The research will also explore how psychosocial resources might help mitigate these risks. Participants will provide information on their childhood experiences, reproductive health, and other relevant factors through surveys and follow-up visits.

Who could benefit from this research

Good fit: Ideal candidates for this research are Black/African American women aged 23-34 who have not been clinically diagnosed with fibroids.

Not a fit: Patients outside the specified age range or those who have already been diagnosed with fibroids may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention strategies for uterine fibroids, particularly in high-risk populations.

How similar studies have performed: Previous research has indicated a correlation between early life adversities and various health outcomes, suggesting that this approach may yield valuable insights.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.