NIH-funded research R21 grant

The link between drinking water arsenic, blood pressure, and stroke risk.

Official title: Drinking Water Arsenic, Blood Pressure, and Ischemic Stroke in the REGARDS Study

Funded at University of California, San Francisco · NIH-11013666 · Data updated 2026-11-12

This study is looking at how drinking water with arsenic might affect blood pressure and the chances of having a stroke, and it's for people from all walks of life across the U.S. who want to understand the health risks linked to arsenic in their water.

More Stroke research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startJanuary 22, 2024
Project endJuly 31, 2025
Funding year2023
Award (this year)$86,262
NIH project number7R21HL159574-03
Project IDNIH-11013666 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals from the REGARDS Study, particularly those living in areas with known arsenic contamination in drinking water.

Less likely to help

Patients who do not consume drinking water from sources with arsenic contamination may not benefit from this research.

What this research studies

This research investigates how exposure to arsenic in drinking water may affect blood pressure and the risk of ischemic stroke among participants in the REGARDS Study, which includes a diverse group of individuals from across the United States. By integrating various data sources, including water quality data and health outcomes, the study aims to uncover potential health impacts related to arsenic exposure. The research will analyze differences in responses based on factors such as sex and race, providing a comprehensive understanding of the issue.

Why it matters

Potential benefit: If successful, this research could lead to improved public health recommendations and interventions to reduce stroke risk associated with arsenic exposure in drinking water.

How similar studies have gone: Previous research has shown associations between drinking water contaminants and health outcomes, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Gribble, Matthew O. — University of California, San Francisco
  • Study coordinator: Gribble, Matthew O.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.