NIH-funded research NIH-funded research

The impact of wheezing in preschool children on their brain development

Official title: Childhood Allergy and the NeOnatal Environment in St Louis (CANOE-STL) and the Impact of Wheezing Illnesses on Neurocognitive Development of Preschool Children

Funded at Washington University · NIH-11319105 · Data updated 2026-11-12

This study is looking at how repeated wheezing in young kids might impact their thinking and feelings as they grow, and it’s for parents of preschoolers who have had wheezing issues.

More Allergy research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWashington University
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startSeptember 1, 2023
Project endMay 31, 2030
Funding year2025
Award (this year)$1,488,322
NIH project number4UH3OD035521-03
Project IDNIH-11319105 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are preschool children aged 1-5 years who experience recurrent wheezing or related respiratory issues.

Less likely to help

Patients who do not experience wheezing or have no respiratory issues may not benefit from this research.

What this research studies

This research investigates how recurrent wheezing illnesses in preschool children affect their neurocognitive and emotional development. It aims to understand the relationship between wheezing, its treatments, and critical brain development during early childhood. By analyzing data from the ECHO cohort study and considering factors like prenatal conditions and socioeconomic status, the study seeks to provide insights into how these elements influence children's health outcomes. The research will involve collecting and analyzing neurodevelopmental measures in young children who experience wheezing.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of wheezing illnesses, potentially enhancing cognitive and emotional development in affected children.

How similar studies have gone: Previous research has indicated significant neurocognitive impacts from chronic health conditions, suggesting that this study's approach could yield valuable insights.

Where this research is happening

  • Washington University
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: Rivera-Spoljaric, Katherine — Washington University
  • Study coordinator: Rivera-Spoljaric, Katherine

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.