The impact of stress and inflammation on the quality of life for long-term breast cancer survivors
Official title: Stress, inflammation, and health-related quality of life of long-term breast cancer survivors
Funded at Stanford University · NIH-10869249 · Data updated 2026-11-12
This study is looking at how stress and inflammation affect the quality of life for long-term breast cancer survivors, especially considering how different backgrounds might change their experiences, and it involves talking to participants about their health and feelings.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | June 1, 2024 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $396,543 |
| NIH project number | 1R21CA290430-01 |
| Project ID | NIH-10869249 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are long-term breast cancer survivors, particularly those from African American, Asian American, and Hispanic backgrounds.
✕Less likely to help
Patients who are not breast cancer survivors or those who have recently been diagnosed may not benefit from this research.
What this research studies
This research investigates how stress and inflammation affect the health-related quality of life (HRQOL) of long-term breast cancer survivors. It focuses on both individual-level stressors, such as treatment-related symptoms, and neighborhood-level stressors that may impact these survivors differently based on their racial and ethnic backgrounds. By examining a diverse cohort of breast cancer survivors, the study aims to identify the unique challenges faced by various groups and how these challenges influence their overall well-being. Participants will be involved in interviews and questionnaires to gather data on their experiences and health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved support and interventions for breast cancer survivors, enhancing their quality of life.
How similar studies have gone: Previous research has shown that addressing both individual and neighborhood-level stressors can significantly improve health outcomes for cancer survivors, suggesting a promising approach in this study.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: John, Esther M. — Stanford University
- Study coordinator: John, Esther M.
Related research
Other NIH-funded projects on the same topics.
-
Cancer Pain Management for Asian American Breast Cancer Survivors with Depressive Symptoms
A technology-based program helps Asian American breast cancer survivors with depressive symptoms manage chronic pain more effectively from home using a web app and mobile tools.
-
Acupuncture for psychic and neural symptoms in breast cancer survivors
A study tests whether acupuncture helps improve joint pain, fatigue, and sleep problems in breast cancer survivors who are on endocrine therapy.
-
Digital tool to help breast cancer survivors stick to hormone therapy
A patient-friendly digital program is being developed to help women with breast cancer take their prescribed hormone therapy more consistently.
-
Fit2ThriveMIND: An at-home program to boost activity with mindfulness for breast cancer survivors
A mobile-based program helps breast cancer survivors add more physical activity through mindful lessons and social support.
-
TOPS for Breast Cancer Survivors: a weight loss program retooled for people living with breast cancer
A Duke-led program is testing a structured weight‑loss plan tailored for breast cancer survivors to help them lose weight and reduce heart disease risk.
-
How heat waves and air pollution affect heart and lung health after breast cancer treatment
This project looks at whether heat events and poor air quality make heart and lung problems more likely for people who survived breast cancer.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.