The impact of speaking two languages on brain health in American Indian adults

Bilingualism as a protective factor of ADRD in American Indian adults: the Strong Heart Study

NIH-funded research Huntington Medical Research Institutes · NIH-11159322

This study is looking at how speaking two languages might help American Indian adults keep their minds sharp and lower the risk of Alzheimer's and other memory problems as they age.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHuntington Medical Research Institutes NIH-funded
Lab location1 site (Pasadena, UNITED STATES)
Project IDNIH-11159322 on NIH RePORTER

What this research studies

This research investigates how bilingualism may serve as a protective factor against Alzheimer's disease and related dementias (ADRD) in American Indian adults. It aims to understand the relationship between speaking two languages and cognitive performance, considering various factors such as age, socioeconomic status, and cultural background. By assessing these relationships, the study seeks to identify how bilingualism can enhance cognitive reserve and potentially reduce the risk of cognitive decline. Participants will be evaluated on their language use and cognitive abilities to provide insights into the benefits of bilingualism in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are American Indian adults aged 65 and older who are bilingual.

Not a fit: Patients who are monolingual or younger than 65 years old may not receive benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to strategies that leverage bilingualism to improve cognitive health and reduce the risk of dementia in American Indian adults.

How similar studies have performed: Previous research has shown that bilingualism can enhance cognitive reserve in various populations, suggesting potential for similar benefits in American Indian adults.

Where this research is happening

Pasadena, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.