The impact of poor sleep on heart health in World Trade Center responders
Official title: Disturbed sleep and cardiovascular outcomes in World Trade Center Responders
Funded at Rutgers Biomedical and Health Sciences · NIH-10905976 · Data updated 2026-11-12
This study is looking at how sleep problems, especially from obstructive sleep apnea, impact heart health in people who responded to the World Trade Center disaster, and it will check if certain blood markers can help predict heart issues in them.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project start | July 1, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $499,998 |
| NIH project number | 5U01OH012634-02 |
| Project ID | NIH-10905976 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are World Trade Center responders experiencing disturbed sleep or symptoms of obstructive sleep apnea.
✕Less likely to help
Patients who do not have a history of sleep disturbances or cardiovascular issues may not benefit from this research.
What this research studies
This research investigates how disturbed sleep, particularly due to obstructive sleep apnea (OSA), affects cardiovascular health in responders to the World Trade Center disaster. It aims to understand the prevalence of different sleep phenotypes among these individuals and how they relate to cardiovascular risks, specifically major adverse cardiovascular events (MACE). By analyzing plasma biomarkers like highly sensitive C-reactive protein (hs-CRP), the study seeks to determine if these biomarkers can predict cardiovascular outcomes in this unique population. Participants will undergo assessments to evaluate their sleep patterns and cardiovascular health.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cardiovascular risks associated with poor sleep in World Trade Center responders.
How similar studies have gone: Previous studies have shown associations between sleep apnea and cardiovascular risks, indicating that this research builds on established findings.
Where this research is happening
-
Rutgers Biomedical and Health Sciences
Newark, United States Active
Researchers
- Principal investigator: Sunderram, Jag — Rutgers Biomedical and Health Sciences
- Study coordinator: Sunderram, Jag
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.