The impact of perceived racism on brain health and Alzheimer's risk in older Black adults

Perceived racism, cardiovascular disease risk, and neurocognitive aging

NIH-funded research Boston University Medical Campus · NIH-11167232

This study is looking at how experiences of racial discrimination might impact brain health in older Black adults, especially in areas of the brain related to memory, to better understand how these experiences could affect aging and the risk of conditions like Alzheimer's disease.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston University Medical Campus NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11167232 on NIH RePORTER

What this research studies

This research investigates how experiences of racial discrimination may affect brain health, particularly focusing on the medial temporal hippocampal region, in older Black adults. It aims to explore the relationship between chronic racial stress and changes in brain structure, such as hippocampal atrophy and white matter hyperintensities, which are linked to Alzheimer's disease and related dementias. By examining these factors, the study seeks to understand how racial identity and experiences of discrimination influence cognitive aging and overall brain health.

Who could benefit from this research

Good fit: Ideal candidates for this research are self-identified Black older adults who may have experienced racial discrimination.

Not a fit: Patients who do not identify as Black or who are not older adults may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for Alzheimer's disease risk among Black older adults.

How similar studies have performed: While research on racial discrimination and health outcomes is growing, this specific focus on racial salience and its effects on brain health in older Black adults is relatively novel.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.