The impact of HIV medications on heart health
Cardiovascular Risk of Antiretroviral Therapy Drugs in HIV
This study is looking at how the medications used to treat HIV might affect heart health, especially focusing on a condition that can cause serious heart problems, and it's for people living with HIV who want to understand how their treatment could impact their heart.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma Medical Research Foundation NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project ID | NIH-11053535 on NIH RePORTER |
What this research studies
This research investigates how antiretroviral therapy (ART) drugs, which are essential for managing HIV, may contribute to heart problems in people living with HIV. The study focuses on understanding the mechanisms behind cardiac fibrosis, a condition that can lead to sudden death in this population. By examining the role of specific proteins and platelets in the body, the researchers aim to identify whether certain ART regimens increase the risk of heart issues. The ultimate goal is to develop preventive strategies to protect heart health in individuals receiving ART.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are undergoing antiretroviral therapy.
Not a fit: Patients who are not on antiretroviral therapy or those without HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer HIV treatment options that minimize cardiovascular risks for patients.
How similar studies have performed: Previous research has indicated potential cardiovascular risks associated with antiretroviral therapy, suggesting that this area of investigation is both relevant and necessary.
Where this research is happening
Oklahoma City, United States
- Oklahoma Medical Research Foundation — Oklahoma City, United States (Active)
Researchers
- Principal investigator: Ahamed, Jasimuddin — Oklahoma Medical Research Foundation
- Study coordinator: Ahamed, Jasimuddin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.