The impact of glucose fluctuations on brain health in older adults
Glucose instability and neurocognitive outcomes in older adults
This study is looking at how changes in blood sugar levels might impact thinking and memory in older adults, especially those at risk for Alzheimer's, by using special devices to track their glucose levels and see how it relates to their brain health and any symptoms they might experience.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10295921 on NIH RePORTER |
What this research studies
This research investigates how fluctuations in glucose levels affect cognitive health in older adults, particularly those at risk for Alzheimer's disease. Using wearable continuous glucose monitoring technology, the study aims to track glucose patterns in individuals with varying diabetes statuses and assess their relationship with cognitive symptoms and brain imaging results. By identifying risk factors and associations, the research seeks to enhance our understanding of how glucose instability may contribute to cognitive decline and dementia. Participants will be monitored for symptoms like dizziness and difficulty concentrating, and their brain health will be evaluated through advanced imaging techniques.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above, particularly those with diabetes or prediabetes.
Not a fit: Patients who are younger than 65 or do not have any issues with glucose regulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management strategies for glucose levels in older adults, potentially reducing the risk of cognitive decline and dementia.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between glucose levels and cognitive health, suggesting that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Selvin, Elizabeth — Johns Hopkins University
- Study coordinator: Selvin, Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.