The impact of cooling duration on brain recovery in children after cardiac arrest

2/2 Pediatric Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

NIH-funded research Medical University of South Carolina · NIH-10922728

This study is looking at how long to cool down kids' brains after they have a cardiac arrest outside of the hospital, to see if longer cooling times can help them recover better and have a better chance of survival.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMedical University of South Carolina NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-10922728 on NIH RePORTER

What this research studies

This research investigates how different durations of therapeutic hypothermia can affect brain recovery in children who have experienced out-of-hospital cardiac arrest. The study aims to identify the optimal cooling duration that can minimize brain injury and improve survival rates. By using a specific scoring system to assess adaptive behaviors, researchers will evaluate the effectiveness of longer cooling periods compared to standard durations. This approach seeks to enhance the understanding of how to better protect the brain in pediatric patients following cardiac arrest.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who have experienced out-of-hospital cardiac arrest.

Not a fit: Patients who have not experienced cardiac arrest or are outside the age range of 0-11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved survival rates and better neurological outcomes for children who suffer cardiac arrest.

How similar studies have performed: Previous research has shown promising results with therapeutic hypothermia in adults, but this specific approach in pediatric populations is still being explored.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.