The impact of circadian rhythms on dementia in older Latinos
Official title: Circadian Disturbance and Dementia in Latin America
Funded at Massachusetts General Hospital · NIH-10922801 · Data updated 2026-11-12
This study is looking at how changes in sleep and daily routines might affect the risk of developing dementia, especially Alzheimer's, in older Latino adults, and it hopes to find ways to improve their brain health and quality of life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 15, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $695,353 |
| NIH project number | 5R01AG083799-03 |
| Project ID | NIH-10922801 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Latino individuals aged 40 to 80, particularly those at risk for Alzheimer's disease or related dementias.
✕Less likely to help
Patients outside the Latino demographic or those younger than 40 years old may not benefit from this research.
What this research studies
This research investigates how disruptions in circadian rhythms may influence the development and progression of dementia, particularly Alzheimer's disease, in older Latino populations. By analyzing data from a large cohort of Latino participants aged 40 to 80, the study aims to identify modifiable factors related to circadian health that could help prevent or delay dementia. The research will utilize existing databases to explore the relationship between sleep patterns, physical activity, and cognitive health in this demographic. The findings could provide insights into culturally relevant interventions for improving quality of life among older adults.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or delaying dementia in older Latino adults.
How similar studies have gone: While there is substantial evidence linking circadian disturbances to cognitive impairment, this specific focus on Latino populations and their unique circadian health is relatively novel.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Hu, Kun — Massachusetts General Hospital
- Study coordinator: Hu, Kun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.