NIH-funded research R01 grant

The impact of blood pressure changes on stroke recovery

Official title: Blood Pressure Variability and Ischemic Stroke Outcome (BP-VISO)

Funded at Yale University · NIH-11001554 · Data updated 2026-11-12

This study is looking at how changes in blood pressure after a stroke can impact how well patients recover, and it’s for people who have had an acute ischemic stroke.

More Stroke research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startJanuary 1, 2023
Project endDecember 31, 2027
Funding year2025
Award (this year)$470,792
NIH project number5R01NS130189-03
Project IDNIH-11001554 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who have experienced an acute ischemic stroke, particularly those with anterior circulation strokes.

Less likely to help

Patients who have not had a stroke or those with other types of strokes may not benefit from this research.

What this research studies

This research investigates how fluctuations in blood pressure after an acute ischemic stroke affect recovery outcomes. By enrolling patients who have experienced a stroke, the study aims to measure blood pressure variability and its relationship to functional recovery. The research will use portable MRI technology to assess brain damage and changes over time, and bedside tests to understand the role of the autonomic nervous system in blood pressure regulation. Ultimately, the goal is to identify effective strategies to manage blood pressure variability in stroke patients.

Why it matters

Potential benefit: If successful, this research could lead to improved recovery strategies for stroke patients by managing blood pressure variability.

How similar studies have gone: Previous research has indicated a correlation between blood pressure variability and stroke outcomes, but this study aims to provide more definitive evidence through a novel prospective approach.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: De Havenon, Adam H. — Yale University
  • Study coordinator: De Havenon, Adam H.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.