The impact of air pollution on Alzheimer's disease in Mexican Americans
Air Pollution, Metabolome, and Alzheimer disease in Mexican Americans
This study is looking at how air pollution might increase the chances of developing Alzheimer's disease and memory problems in Mexican Americans, using blood samples collected over ten years to find out what changes happen in the body due to pollution.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10591306 on NIH RePORTER |
What this research studies
This research investigates how exposure to air pollution affects the risk of developing Alzheimer's disease and cognitive impairment among Mexican Americans. By analyzing blood samples collected over a decade from a large cohort, the study aims to uncover biological changes linked to air pollution exposure and its relationship with Alzheimer's disease. The researchers will utilize advanced metabolomics techniques to identify specific metabolic changes that may indicate the onset and progression of cognitive decline. This approach will help in understanding the mechanisms behind the disease and potentially lead to preventive strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are elderly Mexican Americans who may be at risk for cognitive impairment or Alzheimer's disease.
Not a fit: Patients who are not of Mexican descent or those who do not have concerns related to cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for Alzheimer's disease in populations disproportionately affected by air pollution.
How similar studies have performed: Previous research has indicated a link between air pollution and cognitive decline, suggesting that this approach may yield valuable insights into Alzheimer's disease.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Ritz, Beate R. — University of California Los Angeles
- Study coordinator: Ritz, Beate R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.