NIH-funded research R01 grant

The impact of air pollution and heat on kidney health in women in Central America

Official title: Air pollutants, heat exposure, and kidney health: A longitudinal study in women in Central America

Funded at University of Colorado Denver · NIH-11053631 · Data updated 2026-11-12

This study is looking at how air pollution and heat might impact the kidney health of women working in agriculture, especially sugarcane fields in Central America, by tracking 200 female workers over three years to see how these environmental factors could affect their health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startApril 1, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$590,989
NIH project number5R01ES034042-03
Project IDNIH-11053631 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women working in agricultural settings in Guatemala and Nicaragua, particularly those exposed to high levels of air pollution.

Less likely to help

Patients who do not work in agricultural environments or are not exposed to significant air pollutants may not benefit from this research.

What this research studies

This research investigates how exposure to air pollutants and heat affects kidney health in women, particularly those working in agriculture in Central America. The study will monitor airborne contaminants and their potential link to kidney injury and inflammation over three years, focusing on 200 female sugarcane workers. Participants will undergo repeated monitoring during high exposure periods to assess the relationship between environmental factors and kidney health outcomes.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for chronic kidney disease in at-risk women.

How similar studies have gone: While there has been significant research on kidney disease in males, this approach focusing on women and air pollution is relatively novel and has not been extensively tested.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Newman, Lee S — University of Colorado Denver
  • Study coordinator: Newman, Lee S

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.