The effects of ultra-processed foods on gut health and blood sugar in middle-aged adults

Ultra-processed food consumption, gut microbiota, and glucose homeostasis in mid-life adults

NIH-funded research Virginia Polytechnic Inst and St Univ · NIH-10618337

This study is looking at how eating a lot of ultra-processed foods affects gut health and blood sugar levels in adults aged 45 to 65, to help understand how diet might play a role in preventing type 2 diabetes.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionVirginia Polytechnic Inst and St Univ NIH-funded
Lab location1 site (Blacksburg, United States)
Project IDNIH-10618337 on NIH RePORTER

What this research studies

This research investigates how consuming ultra-processed foods affects gut microbiota and glucose regulation in adults aged 45 to 65. It aims to understand the relationship between diet, gut health, and the risk of developing type 2 diabetes, particularly in mid-life adults who may be more vulnerable to these effects. The study will involve monitoring dietary intake and analyzing changes in gut bacteria, inflammation levels, and blood sugar control over a specified period. By establishing these connections, the research seeks to lay the groundwork for future interventions aimed at preventing diabetes.

Who could benefit from this research

Good fit: Ideal candidates for this research are middle-aged adults between 45 and 65 years old who consume a diet high in ultra-processed foods.

Not a fit: Patients who are younger than 45 years or those who do not consume ultra-processed foods may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to dietary recommendations that help prevent type 2 diabetes in middle-aged adults.

How similar studies have performed: Previous research has shown links between ultra-processed food consumption and health issues, but this specific investigation into mid-life adults is novel.

Where this research is happening

Blacksburg, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.