The effects of prescription opioids on cognitive decline in older adults
Prescription opioids, cognitive decline, and Alzheimer's disease in older adults
This study is looking at how taking prescription opioids might affect thinking and memory in older adults over 65, and it wants to hear from them about their experiences with these medications for pain relief.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11021085 on NIH RePORTER |
What this research studies
This research investigates how the use of prescription opioids affects cognitive function in older adults, particularly those over 65 years of age. It aims to evaluate the relationship between opioid use and changes in cognitive abilities over time, as well as the impact on brain structure. Additionally, the study will gather insights from older adults about their experiences with opioids for pain management and its effects on their cognition. By understanding these relationships, the research seeks to inform better pain management strategies for older patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who are experiencing chronic pain and are currently using prescription opioids.
Not a fit: Patients who are younger than 65 years or those not using prescription opioids for pain management may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies that minimize cognitive decline in older adults.
How similar studies have performed: Previous studies have indicated a potential link between opioid use and cognitive decline, suggesting that this research could build on existing findings.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Warner, Nafisseh S — Mayo Clinic Rochester
- Study coordinator: Warner, Nafisseh S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.