The effects of prenatal exposure to certain chemicals on thyroid health and autism risk.
Prenatal Exposure to NIS inhibitors, Iodine Deficiency, and Thyroid Dysfunction
This study is looking at how certain chemicals that pregnant women might be exposed to can affect their thyroid health and possibly increase the chances of their children developing autism.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor University NIH-funded |
| Lab location | 1 site (Waco, United States) |
| Project ID | NIH-10668541 on NIH RePORTER |
What this research studies
This research investigates how exposure to specific environmental chemicals during pregnancy may affect thyroid function and increase the risk of autism spectrum disorder (ASD) in children. It focuses on the impact of substances that inhibit iodide uptake, which is crucial for thyroid hormone production. By analyzing data from a large epidemiological project, the study aims to establish a link between maternal thyroid dysfunction and the development of ASD in offspring. The methodology includes assessing maternal exposure levels and thyroid health indicators.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women who may have been exposed to environmental chemicals that affect thyroid function.
Not a fit: Patients who are not pregnant or those who do not have children at risk for autism may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for autism spectrum disorder linked to prenatal environmental exposures.
How similar studies have performed: Previous research has indicated a connection between maternal thyroid health and neurodevelopmental outcomes, suggesting that this approach is grounded in established findings.
Where this research is happening
Waco, United States
- Baylor University — Waco, United States (Active)
Researchers
- Principal investigator: Shin, Hyeong-Moo — Baylor University
- Study coordinator: Shin, Hyeong-Moo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.