The effects of estrogen receptors and inflammation on cognitive health in women with HIV.

Women Living with HIV: Cognitive Impact of Estrogen Receptors, Inflammation, and Aging

NIH-funded research Virginia Commonwealth University · NIH-10909991

This study is looking at how estrogen and inflammation affect memory and thinking skills in older women with HIV, aiming to understand how changes in hormone levels during menopause might influence their brain health.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionVirginia Commonwealth University NIH-funded
Lab location1 site (Richmond, United States)
Project IDNIH-10909991 on NIH RePORTER

What this research studies

This research investigates how estrogen receptors and inflammation impact cognitive decline in women living with HIV. It focuses on understanding the relationship between estrogen levels, menopause, and cognitive health, particularly in older women. By analyzing blood samples from participants, the study aims to identify how changes in estrogen receptor expression may predict cognitive outcomes. The research leverages data from the Atlanta Women's Interagency HIV Study to explore these connections in depth.

Who could benefit from this research

Good fit: Ideal candidates for this research are women living with HIV, particularly those who are older and may be experiencing menopause.

Not a fit: Patients who are not living with HIV or who are male may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing cognitive decline in women living with HIV.

How similar studies have performed: Previous research has shown that hormonal factors can influence cognitive health, suggesting that this study's approach may yield valuable insights.

Where this research is happening

Richmond, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAlzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.