The effects of e-cigarettes on oral health and bacteria

E-cigarettes and perturbations in the subgingival ecosystem

NIH-funded research University of Michigan at Ann Arbor · NIH-10690240

This study is looking at how using e-cigarettes might change the bacteria in your mouth and affect your overall oral health, so we can better understand what it means for your smile and wellbeing.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-10690240 on NIH RePORTER

What this research studies

This research investigates how electronic nicotine delivery systems (e-cigarettes) affect the oral microbiome and overall oral health. It aims to understand the biological impacts of e-cigarettes, particularly focusing on how they alter the balance of bacteria in the mouth and influence host immunity. By employing advanced clinical study designs and integrated 'omics' approaches, the research will analyze the changes in the oral ecosystem caused by e-cigarette use. This comprehensive approach combines clinical outcomes with laboratory investigations to provide a clearer picture of the health implications of e-cigarettes.

Who could benefit from this research

Good fit: Ideal candidates for this research include adolescents and young adults who use e-cigarettes and are concerned about their oral health.

Not a fit: Patients who do not use e-cigarettes or have pre-existing severe oral health conditions unrelated to e-cigarette use may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a better understanding of the health risks associated with e-cigarette use, particularly regarding oral health.

How similar studies have performed: While there is limited research specifically on e-cigarettes and oral health, studies on smoking and oral microbiomes suggest that similar approaches could yield significant insights.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.