The effects of cytomegalovirus infection on fetal immune development
CMV infection impact on placental immunometabolism and fetal immunity
This study is looking at how a mother’s cytomegalovirus (CMV) infection during pregnancy might affect her baby’s immune system and metabolism, helping us understand how the virus could change things even if it doesn’t directly infect the baby.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-10873959 on NIH RePORTER |
What this research studies
This research investigates how maternal cytomegalovirus (CMV) infection during pregnancy influences the immune system and metabolism of the fetus. Using a nonhuman primate model, the study aims to understand the mechanisms by which maternal CMV exposure may alter immune cell populations and metabolic pathways at the maternal-fetal interface. The research will explore both direct effects of CMV transmission and potential impacts even in cases where the virus does not infect the fetus. By examining these interactions, the study seeks to fill critical gaps in knowledge regarding fetal immunity and development.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women, particularly those who are CMV-seronegative or have a history of CMV infection.
Not a fit: Patients who are not pregnant or those who are not affected by CMV may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of congenital infections and better strategies for managing maternal health during pregnancy.
How similar studies have performed: Previous research has shown significant impacts of viral infections on immune development, suggesting that this approach may yield valuable insights.
Where this research is happening
New Orleans, United States
- Tulane University of Louisiana — New Orleans, United States (Active)
Researchers
- Principal investigator: Kaur, Amitinder — Tulane University of Louisiana
- Study coordinator: Kaur, Amitinder
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.