The effects of chronic HIV infection on eye diseases
Official title: Chronic HIV infection and ischemic retinopathies
Funded at Augusta University · NIH-11039513 · Data updated 2026-11-12
This study is looking at how living with chronic HIV and taking anti-HIV medications might affect eye health, specifically how they could lead to serious eye problems that can cause blindness, and it aims to find ways to prevent these issues for people with HIV.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Augusta University NIH-funded |
| Lab location | 1 site (Augusta, United States) |
| Project start | February 1, 2025 |
| Project end | January 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $231,000 |
| NIH project number | 1R21EY037078-01 |
| Project ID | NIH-11039513 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals living with HIV who are experiencing or at risk for ischemic retinopathies.
✕Less likely to help
Patients who do not have HIV or those without any risk factors for ischemic retinopathies may not benefit from this research.
What this research studies
This research investigates how chronic HIV infection and the use of anti-HIV drugs may contribute to the development and worsening of eye diseases known as ischemic retinopathies, which can lead to blindness. The study focuses on understanding the relationship between chronic inflammation caused by HIV and the resulting neurovascular dysfunction that accelerates aging in the eyes. By examining both experimental models and patient data, the research aims to identify risk factors and mechanisms that could help in preventing these serious eye conditions in people living with HIV.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing vision loss in individuals with chronic HIV infection.
How similar studies have gone: While the specific focus on ischemic retinopathies in the context of chronic HIV is novel, related research has shown that chronic inflammation can significantly impact eye health in other populations.
Where this research is happening
-
Augusta University
Augusta, United States Active
Researchers
- Principal investigator: Bartoli, Manuela — Augusta University
- Study coordinator: Bartoli, Manuela
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.