The effects of cannabis use on inflammation in HIV patients

Cannabis use frequency and its impact on monocyte-mediated inflammation in HIV patients

['FUNDING_R01'] · MICHIGAN STATE UNIVERSITY · NIH-10875505

This study is looking at how using cannabis in different amounts might affect inflammation and brain health in people living with HIV, especially those dealing with memory and thinking issues, to see if it could help improve their condition.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMICHIGAN STATE UNIVERSITY (nih funded)
Locations1 site (EAST LANSING, UNITED STATES)
Trial IDNIH-10875505 on ClinicalTrials.gov

What this research studies

This research investigates how different frequencies of cannabis use impact inflammation mediated by monocytes in patients living with HIV. The study focuses on understanding the relationship between cannabis consumption and neuroinflammation, which is a significant concern for HIV patients, particularly those experiencing neurocognitive disorders. By examining the activation of monocytes and their role in inflammation, the research aims to uncover potential therapeutic benefits of cannabis in managing HIV-related complications. Patients may be monitored for changes in inflammatory markers and cognitive function as part of the study.

Who could benefit from this research

Good fit: Ideal candidates for this research are HIV-positive individuals who are experiencing neurocognitive impairments and are open to discussing their cannabis use.

Not a fit: Patients who are not HIV-positive or those who do not use cannabis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic strategies for reducing inflammation and improving cognitive health in HIV patients.

How similar studies have performed: Previous research has shown promising results regarding the anti-inflammatory effects of cannabis, suggesting that this approach may yield beneficial outcomes for HIV patients.

Where this research is happening

EAST LANSING, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immune Deficiency Syndrome related dementia, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.