NIH-funded research R21 grant

The effects of alcohol on muscle health in older adults

Official title: Alcohol and dysfunctional skeletal muscle mass: implications in aging

Funded at Lsu Health Sciences Center · NIH-10932364 · Data updated 2026-11-12

This study looks at how drinking alcohol might affect muscle strength and function in older adults over 60, helping us understand how it can lead to weakness and less physical ability, so we can find ways to reduce these risks for healthier aging.

More Aging research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionLsu Health Sciences Center
NIH-funded
Lab location1 site (New Orleans, United States)
Project startSeptember 20, 2023
Project endAugust 31, 2025
Funding year2024
Award (this year)$219,612
NIH project number5R21AA030869-02
Project IDNIH-10932364 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals aged 60 and older, with or without a history of alcohol use, and without significant underlying health conditions.

Less likely to help

Patients under the age of 60 or those with severe comorbidities may not benefit from this research.

What this research studies

This research investigates how alcohol consumption affects skeletal muscle strength and function in older adults, particularly those over 60 years of age. It aims to understand the mechanisms behind alcohol-related myopathy, which can lead to frailty and decreased physical performance. By comparing individuals who consume alcohol with those who do not, the study seeks to uncover the impact of alcohol on mitochondrial function and overall muscle health. The findings could help identify strategies to mitigate the risks associated with alcohol use in aging populations.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for maintaining muscle health and reducing frailty in older adults who consume alcohol.

How similar studies have gone: Previous research has shown that alcohol can negatively impact muscle health, but this specific focus on aging and mitochondrial function is relatively novel.

Where this research is happening

  • Lsu Health Sciences Center
    New Orleans, United States
    Active

Researchers

  • Principal investigator: Simon, Liz — Lsu Health Sciences Center
  • Study coordinator: Simon, Liz

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.