The effects of air pollution on progressive pulmonary fibrosis
Air Pollution, Environmental Injustice and Progressive Pulmonary Fibrosis
This study is looking at how air pollution, especially tiny particles and nitrogen dioxide, might lead to a serious lung condition called progressive pulmonary fibrosis, particularly in people living in areas that are more vulnerable to pollution.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11053723 on NIH RePORTER |
What this research studies
This research investigates how exposure to air pollution, particularly fine particulate matter and nitrogen dioxide, may contribute to the development of progressive pulmonary fibrosis (PPF), a severe lung condition. The study focuses on individuals living in areas with high social vulnerability, who may face greater exposure to harmful air pollutants. By utilizing geospatial mapping and advanced modeling techniques, the research aims to uncover the relationship between environmental factors and the incidence of PPF. The findings could lead to better understanding and potential interventions for at-risk populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living in areas with high levels of air pollution and those diagnosed with interstitial lung disease.
Not a fit: Patients who do not live in polluted environments or those without any lung disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies and treatment options for patients at risk of progressive pulmonary fibrosis due to air pollution.
How similar studies have performed: Previous research has indicated a link between air pollution and lung diseases, suggesting that this approach could yield significant insights into PPF, although the specific focus on PPF in relation to environmental injustice is relatively novel.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Macmurdo, Maeve Georgia — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Macmurdo, Maeve Georgia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.