The effects of air pollution and noise on dementia risk and brain health
Air pollution and noise exposures in relation to dementia: from brain imaging markers to clinical disease
This study is looking at how air pollution and noise might affect brain health and increase the risk of Alzheimer's and other memory problems in older adults, using brain scans to see how these factors work together.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10574492 on NIH RePORTER |
What this research studies
This research investigates how exposure to air pollution and ambient noise may contribute to cognitive decline and increase the risk of Alzheimer's disease and related dementias in older adults. By utilizing advanced brain imaging techniques, the study aims to uncover the mechanisms through which these environmental factors affect brain health. The research will also explore whether these exposures interact with each other to amplify their effects on cognitive function. Participants may undergo assessments that include brain imaging and health evaluations to better understand these relationships.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who may be experiencing cognitive decline or are at risk for Alzheimer's disease.
Not a fit: Patients with pre-existing severe cognitive impairment or those not residing in areas with significant air pollution or noise exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to public health interventions that reduce exposure to harmful environmental factors, potentially lowering the risk of dementia.
How similar studies have performed: Previous studies have indicated a link between environmental exposures and cognitive decline, but this research aims to provide more definitive evidence and explore novel interactions.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Weuve, Jennifer — Boston University Medical Campus
- Study coordinator: Weuve, Jennifer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.