The connection between oral bacteria, gum disease, and HPV infection in people with HIV
Oral microbiome and periodontal diseases in oral HPV infection among people living with HIV
This study is looking at how the bacteria in your mouth and gum diseases might affect HPV infections in people living with HIV, and it wants to learn how social factors play a role in this, so we can better understand why HPV-related cancers are more common in this group.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10894827 on NIH RePORTER |
What this research studies
This research investigates how the oral microbiome and periodontal diseases influence oral HPV infections in individuals living with HIV. It aims to understand the immune responses related to these infections and explore how social factors may affect the oral microbiome and HPV prevalence. By examining the interactions between oral health and HPV, the study seeks to uncover the underlying mechanisms that contribute to higher rates of HPV-related cancers in this population. Participants may undergo assessments of their oral health and microbiome to provide valuable data for the research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who may also be experiencing oral health issues or are at risk for HPV infections.
Not a fit: Patients who do not have HIV or those without any oral health concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for oral HPV infections and related cancers in people living with HIV.
How similar studies have performed: While the specific interactions between the oral microbiome and HPV in people with HIV are not well-studied, related research has shown promising results in understanding oral health impacts on viral infections.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Xiao, Canhua — Emory University
- Study coordinator: Xiao, Canhua
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.