Testing urine samples for HPV and cervical cancer screening in women with HIV in Malawi and South Africa
Project 1: Urine sampling for HPV infection and methylation testing for cervical cancer screening among women living with HIV in Malawi and South Africa
This study is looking at whether testing urine samples can help check for HPV and cervical cancer in women living with HIV in Malawi and South Africa, making it easier and more affordable for them to get screened.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10891543 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of using urine samples to test for HPV infection and methylation as a method for cervical cancer screening among women living with HIV in Malawi and South Africa. The study aims to provide a cost-effective and scalable screening approach, particularly in clinical settings where traditional pelvic examinations are not feasible. By validating urine-based HPV testing, the research seeks to improve cervical cancer screening coverage for HIV-positive women, who are at a higher risk for cervical cancer. The project will be conducted at established cervical screening clinics in the two countries.
Who could benefit from this research
Good fit: Ideal candidates for this research are women living with HIV in Malawi and South Africa who are at risk for cervical cancer.
Not a fit: Patients who are not living with HIV or those who do not reside in Malawi or South Africa may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance cervical cancer screening accessibility and early detection for women living with HIV.
How similar studies have performed: Previous research has shown promise in using alternative sampling methods for HPV testing, indicating potential success for this approach.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Chibwesha, Carla J — Univ of North Carolina Chapel Hill
- Study coordinator: Chibwesha, Carla J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.