Testing safety and effects of antibodies in infants exposed to HIV-1
OPEN-LABEL PHASE I STUDY OF THE SAFETY AND PHARMACOKINETICS OF NEUTRALIZING MONOCLONAL ANTIBODIES IN INFANTS EXPOSED TO HIV-I
This study is looking at how safe and effective a new treatment with special antibodies is for infants who have been exposed to HIV-1, and it's designed to help find better ways to prevent and treat HIV in young kids.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Westat, INC. NIH-funded |
| Lab location | 1 site (Rockville, United States) |
| Project ID | NIH-11181769 on NIH RePORTER |
What this research studies
This research investigates the safety and pharmacokinetics of neutralizing monoclonal antibodies in infants who have been exposed to HIV-1. The study is part of a larger effort by the International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) to evaluate potential therapies for HIV in young populations. Participants will be monitored closely to assess how well their bodies process these antibodies and to ensure their safety during the treatment. The research aims to improve prevention and treatment strategies for HIV in infants and children.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants who have been exposed to HIV-1, particularly those under the age of 12 months.
Not a fit: Patients who are not infants or those who have not been exposed to HIV-1 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatments for infants exposed to HIV-1.
How similar studies have performed: Previous research has shown promise in using monoclonal antibodies for treating HIV, indicating a potential for success in this approach.
Where this research is happening
Rockville, United States
- Westat, INC. — Rockville, United States (Active)
Researchers
- Principal investigator: Driver, Barbara — Westat, INC.
- Study coordinator: Driver, Barbara
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.