Testing pain responses in patients with chronic pancreatitis
Official title: P-QST Project: Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis
Funded at University of Pittsburgh at Pittsburgh · NIH-10877786 · Data updated 2026-11-12
This study is looking at a special test that helps doctors figure out which people with chronic pancreatitis are likely to find relief from their pain treatments, so they can create more tailored plans to help manage their discomfort.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | July 1, 2021 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $567,562 |
| NIH project number | 5R01DK127042-04 |
| Project ID | NIH-10877786 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with chronic pancreatitis who experience significant abdominal pain.
✕Less likely to help
Patients without chronic pancreatitis or those whose pain is not related to pancreatic issues may not benefit from this research.
What this research studies
This research investigates how a specialized test called Pancreatic Quantitative Sensory Testing (P-QST) can help predict which patients with chronic pancreatitis will respond to pain relief treatments. By using standardized methods to assess how patients perceive pain, the study aims to categorize patients based on their pain processing abilities. This could lead to more personalized treatment plans, improving outcomes for those suffering from debilitating abdominal pain. The research will involve evaluating patients' responses to various pain stimuli to better understand their condition.
Why it matters
Potential benefit: If successful, this research could lead to more effective pain management strategies for patients with chronic pancreatitis.
How similar studies have gone: Previous research has shown that similar quantitative sensory testing approaches have been successful in other pain conditions, suggesting potential for this method in chronic pancreatitis.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Phillips, Anna Evans — University of Pittsburgh at Pittsburgh
- Study coordinator: Phillips, Anna Evans
Related research
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UPMC Center for Pancreatitis and Diabetes research program
A specialized center at the University of Pittsburgh is advancing clinical and biological studies of chronic pancreatitis, recurrent acute pancreatitis, and diabetes to improve understanding and care.
-
Chronic Pancreatitis Research Network to Understand Symptoms and Find Treatments
This project advances studies of chronic pancreatitis to understand why some people progress and to test new ideas that could diagnose or slow the disease.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.